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Laboratories in the Cellular and Molecular Physiology program
focus on basic cellular processes such as intracellular trafficking
of proteins and lipids, protein structure and function, ion
transport, signal transduction pathways, transcriptional,
translational, and post-translational regulation of gene
expression, cell growth control, cytoskeletal dynamics, and
cell migration.
The work of almost every Physiology laboratory touches on the molecular and
cellular basis of human disease. Our labs work on cancer, wound healing, pulmonary
disease, cholestasis, and cellular mechanisms of aging. There is a particular
emphasis on genetic diseases such as cystic fibrosis, polycystic kidney disease,
and lysosomal storage diseases like Niemann-Pick C, Batten disease and Tay-Sachs
disease, as well as diseases with a genetic component such as hypertension,
diabetes, breast cancer, and Alzheimer's disease.
Physiology labs take an integrative approach to science. Research projects
apply cellular and molecular biology, molecular genetics, and genomics-based
research to the central issues in human development and disease. Functional
genomics approaches are being applied in C. elegans and mouse models of development
and disease. Our labs are developing novel gene- and cell-based therapeutics
that might someday be capable of prolonging life as well as correcting inborn
errors of metabolism, cardiovascular disease, and cancer. The emphasis on human
disease is highlighted by our graduate curriculum. Our mission is to train
outstanding scientists and physician-scientists who will seek careers in academia-
and biotechnology-based biomedical research.
Explore the
program website for more information!
To apply
for admission to the Cellular and Molecular Physiology
program, students must apply through the Integrated
Studies Program. Click
here to apply. |
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