Education | Laboratory Personnel | General Research Interest | Selected Research Projects
Research and Clinical Interests | Major Specialized Equipment Items Available | Selected Publications
TCSVM Faculty

Jean M. Poulson
Assistant Professor
Department of Clinical Sciences
Oncology
Phone: 508-839-5395 x8-4682
Fax: 508-839-7951

Education
Ph.D. - Colorado State University - 2001
DVM - Colorado State University - 1992
BS - Colorado State University - 1989

Board Certification
American College of Veterinary Radiology (Radiation Oncology)

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General Research Interest
Spontaneous animal tumors as models for human and veterinary medicine. Normal tissue response to irradiation alone and in combination with other modalities.

Research Sponsor Interest:

  • Privately Funded Research
  • Federally Funded Research

Selected Research Projects

  • Three Dimensional MRI Based Treatment Planning for Radiation Therapy. Comparison of conventional CT based three-dimensional radiation therapy treatment plans with MR based treatment plans.
  • Intensity Modulated Radiation Therapy (IMRT) for Palliation in Dogs. Investigating whether palliative IMRT yields significant alleviation of clinical signs with fewer side effects that conventional radiation therapy.

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Research and Clinical Interests

  • Palliative and end of life care for veterinary cancer patients.
  • Magnetic resonance three-dimensional treatment planning for radiation therapy.
  • Radiation dose-volume effects in normal tissues, especially lung.
  • Effects of thoracic radiation therapy and pulmonary metastatic disease on pulmonary function.
  • Tumor metabolism, physiology, and immunology.
  • Cytokine mediation of tissue response to irradiation.
  • Hyperthermia for cancer therapy and drug delivery.
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Major Specialized Equipment Items Available

  • Siemens Primus 6MV linear accelerator with 6 - 21 MeV electrons, multi-leaf collimator and intensity modulated radiation therapy (IMRT) capability
  • MRI
  • CT
  • nuclear medicine
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Selected Publications

  1. Siddiqui F, Li CY, LaRue SM, POULSON JM, Avery PR, Pruitt AF, Zhang X, Ullrich RL, Thrall DE, Dewhirst MW, Hauck ML. A phase I trial of hyperthermia-induced interleukin-12 gene therapy in spontaneously arising feline soft tissue sarcomas. Mol Cancer Ther, 6(1): 380-9, 2007.

  2. Lora-Michiels M, Yu D, Sanders L, POULSON JM, Azuma C, Case B, Vujaskovic Z, Thrall DE, Charles HC, Dewhirst MW. Extracellular pH and P-31 magnetic resonance spectroscopic variables are related to outcome in canine soft-tissue sarcomas treated with thermoradiotherapy. Clin Cancer Res, 12(19): 5733-40, 2006.

  3. Hauck ML, LaRue SM, Petros WP, POULSON JM, Yu D, Spasojevic I, Pruitt AF, Klein A, Case B, Thrall DE, Needham D, Dewhirst MW. Phase I trial of doxorubicin-containing low temperature sensitive liposomes in spontaneous canine tumors. Clin Cancer Res, 12(13): 4004-10, 2006.

  4. Thrall DE, LaRue SM, Yu D, Samulski T, Sanders L, Case B, Rosner G, Azuma C, POULSON J, Pruitt AF, Stanley W, Hauck ML, Williams L, Hess P, Dewhirst MW. Thermal dose is related to duration of local control in canine sarcomas treated with thermoradiotherapy. Clin Cancer Res, 11(14): 5602-14, 2005.

  5. POULSON JM, Vujaskovic Z, Gillette SM, Chaney, EL, Gillette EL. Volume and dose-response effects for fatal pneumonitis after fractionated irradiation of canine lung. International Journal of Radiation Biology 76:463-8, 2000.

     

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